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Derivation and maturation of synthetic and contractile vascular smooth muscle cells from human pluripotent stem cells

AIMS: Embryonic vascular smooth muscle cells (vSMCs) have a synthetic phenotype; in adults, they commit to the mature contractile phenotype. Research shows that human pluripotent stem cells (hPSCs) differentiate into vSMCs, but nobody has yet documented their maturation into the synthetic or contrac...

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Hlavní autoři: Wanjare, Maureen, Kuo, Frederick, Gerecht, Sharon
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543989/
https://ncbi.nlm.nih.gov/pubmed/23060134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs315
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