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MiR-34 modulates Caenorhabditis elegans lifespan via repressing the autophagy gene atg9
Evidence for a regulatory role of the miR-34 family in senescence is growing. However, the exact role of miR-34 in aging in vivo remains unclear. Here, we report that a mir-34 loss-of-function mutation in Caenorhabditis elegans markedly delays the age-related physiological decline, extends lifespan,...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer Netherlands
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543738/ https://ncbi.nlm.nih.gov/pubmed/22081425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9324-3 |
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