Smad7 inhibits autocrine expression of TGF-β(2) in intestinal epithelial cells in baboon necrotizing enterocolitis

Preterm infants may be at risk of necrotizing enterocolitis (NEC) due to deficiency of transforming growth factor-β 2 (TGF-β(2)) in the developing intestine. We hypothesized that low epithelial TGF-β(2) expression in preterm intestine and during NEC results from diminished autocrine induction of TGF...

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Hlavní autoři: Namachivayam, Kopperuncholan, Blanco, Cynthia L., MohanKumar, Krishnan, Jagadeeswaran, Ramasamy, Vasquez, Margarita, McGill-Vargas, Lisa, Garzon, Steven A., Jain, Sunil K., Gill, Ravinder K., Freitag, Nancy E., Weitkamp, Jörn-Hendrik, Seidner, Steven R., Maheshwari, Akhil
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Inflammation/Immunity/Mediators
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543645/
https://ncbi.nlm.nih.gov/pubmed/23154975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00141.2012
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