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Autoimmunity to isomerized histone H2B in systemic lupus erythematosus
Histone H2B is a common target of autoantibodies in both spontaneous and drug-induced systemic lupus erythematosus (SLE). Recent studies demonstrate that Asp(25) of histone H2B (H2B) spontaneously converts to an isoaspartic acid (isoAsp) in vivo. Our laboratory has demonstrated that the posttranslat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543506/ https://ncbi.nlm.nih.gov/pubmed/22967069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2012.710859 |
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