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Discovery of biomarker combinations that predict periodontal health or disease with high accuracy from GCF samples based on high-throughput proteomic analysis and mixed-integer linear optimization

AIM: To identify optimal combination(s) of proteomic based biomarkers in gingival crevicular fluid (GCF) samples from chronic periodontitis (CP) and periodontally healthy individuals and validate the predictions through known and blind test sets. MATERIALS AND METHODS: GCF samples were collected fro...

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Detalhes bibliográficos
Main Authors: Baliban, Richard C., Sakellari, Dimitra, Li, Zukui, Guzman, Yannis, Garcia, Benjamin A., Floudas, Christodoulos A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543478/
https://ncbi.nlm.nih.gov/pubmed/23190455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcpe.12037
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