Engineered Drug Resistant γδ T Cells Kill Glioblastoma Cell Lines during a Chemotherapy Challenge: A Strategy for Combining Chemo- and Immunotherapy

Classical approaches to immunotherapy that show promise in some malignancies have generally been disappointing when applied to high-grade brain tumors such as glioblastoma multiforme (GBM). We recently showed that ex vivo expanded/activated γδ T cells recognize NKG2D ligands expressed on malignant g...

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Detalhes bibliográficos
Main Authors: Lamb, Lawrence S., Bowersock, Joscelyn, Dasgupta, Anindya, Gillespie, G. Yancey, Su, Yun, Johnson, Austin, Spencer, H. Trent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543433/
https://ncbi.nlm.nih.gov/pubmed/23326319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051805
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