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MHC Class II-Restricted Presentation of the Major House Dust Mite Allergen Der p 1 Is GILT-Dependent: Implications for Allergic Asthma

Gamma-interferon-inducible lysosomal thiol reductase (GILT) is known to reduce disulfide bonds present in proteins internalized by antigen presenting cells, facilitating optimal processing and presentation of peptides on Major Histocompatibility Complex class II molecules, as well as the subsequent...

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Detalhes bibliográficos
Main Authors: West, Laura Ciaccia, Grotzke, Jeff E., Cresswell, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543425/
https://ncbi.nlm.nih.gov/pubmed/23326313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051343
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