Increased nociceptive sensitivity and nociceptin/orphanin FQ levels in a rat model of PTSD

BACKGROUND: Clinical studies indicate that post-traumatic stress disorder (PTSD) frequently shares co-morbidity with chronic pain. Although in animals acute stress-induced antinociception is well documented, the effect of PTSD-like stress on nociceptive sensitivity is unclear. Though a few studies m...

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Bibliographic Details
Main Authors: Zhang, Yong, Gandhi, Priyam R, Standifer, Kelly M
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543245/
https://ncbi.nlm.nih.gov/pubmed/23082795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-76
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