Nelfinavir is effective in inhibiting the multiplication and aspartic peptidase activity of Leishmania species, including strains obtained from HIV-positive patients

OBJECTIVES: There is a general lack of effective and non-toxic chemotherapeutic agents for leishmaniasis and there is as yet no study about the effect of HIV peptidase inhibitors (HIV PIs) on Leishmania/HIV-coinfected patients. In the present work, we performed a comparative analysis of the spectrum...

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Main Authors: Santos, Lívia O., Vitório, Bianca S., Branquinha, Marta H., Pedroso e Silva, Conceição M., Santos, André L. S., d'Avila-Levy, Claudia M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543121/
https://ncbi.nlm.nih.gov/pubmed/23109184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks410
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