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Identification of a His-Asp-Cys Catalytic Triad Essential for Function of the Rho Inactivation Domain (RID) of Vibrio cholerae MARTX Toxin

Vibrio cholerae is the causative agent of the severe diarrheal disease cholera. For V. cholerae to colonize the intestinal epithelium, accessory toxins such as the multifunctional autoprocessing repeats-in-toxin (MARTX(Vc)) toxin are required. MARTX toxins are composite toxins comprised of arrayed e...

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Autors principals: Ahrens, Sebastian, Geissler, Brett, Satchell, Karla J. F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543022/
https://ncbi.nlm.nih.gov/pubmed/23184949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.396309
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