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Asymmetric Regulation of Bipolar Single-stranded DNA Translocation by the Two Motors within Escherichia coli RecBCD Helicase

Repair of double-stranded DNA breaks in Escherichia coli is initiated by the RecBCD helicase that possesses two superfamily-1 motors, RecB (3′ to 5′ translocase) and RecD (5′ to 3′ translocase), that operate on the complementary DNA strands to unwind duplex DNA. However, it is not known whether the...

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Detalhes bibliográficos
Main Authors: Xie, Fuqian, Wu, Colin G., Weiland, Elizabeth, Lohman, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542991/
https://ncbi.nlm.nih.gov/pubmed/23192341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.423384
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