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RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis

The ubiquitin-proteasome system has numerous crucial roles in physiology and pathophysiology. Fundamental to the specificity of this system are ubiquitin-protein ligases (E3s). Of these, the majority are RING finger and RING finger-related E3s. Many RING finger E3s have roles in processes that are c...

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Dettagli Bibliografici
Autori principali: Lipkowitz, Stanley, Weissman, Allan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542975/
https://ncbi.nlm.nih.gov/pubmed/21863050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3120
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