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Immunoglobulin heavy/light chain ratios improve paraprotein detection and monitoring, identify residual disease and correlate with survival in multiple myeloma patients

The novel heavy/light chain (HLC) assay was used for the detection and measurement of monoclonal immunoglobulins, response evaluation and prognostication. This test allows identification and quantification of the different light chain types of each immunoglobulin class (for example, IgGκ and IgGλ) a...

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Detalhes bibliográficos
Main Authors: Ludwig, H, Milosavljevic, D, Zojer, N, Faint, J M, Bradwell, A R, Hübl, W, Harding, S J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542627/
https://ncbi.nlm.nih.gov/pubmed/22955329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.197
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