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Estimating the Rate of Irreversibility in Protein Evolution
Whether or not evolutionary change is inherently irreversible remains a controversial topic. Some examples of evolutionary irreversibility are known; however, this question has not been comprehensively addressed at the molecular level. Here, we use data from 221 human genes with known pathogenic mut...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3542581/ https://ncbi.nlm.nih.gov/pubmed/23132897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evs096 |
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