Polymorphism of the DNA repair genes RAD51 and XRCC2 in smoking- and drinking-related laryngeal cancer in a Polish population

INTRODUCTION: Cigarette smoke and alcohol can generate reactive oxygen species, which may induce DNA double-strand breaks (DSBs), the most serious DNA lesion. In humans, DSBs are repaired mainly by non-homologous end joining and homologous recombination repair (HRR). Several polymorphisms in the DNA...

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Detalhes bibliográficos
Main Authors: Romanowicz-Makowska, Hanna, Smolarz, Beata, Gajęcka, Marzena, Kiwerska, Katarzyna, Rydzanicz, Malgorzata, Kaczmarczyk, Dariusz, Olszewski, Jurek, Szyfter, Krzysztof, Błasiak, Janusz, Morawiec-Sztandera, Alina
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2012
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542498/
https://ncbi.nlm.nih.gov/pubmed/23319983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2012.32417
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