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An Assay Suitable for High Throughput Screening of Anti-Influenza Drugs

We developed a novel drug screening system for anti-influenza A virus by targeting the M2 proton channel. In the SPP (Single Protein Production) system, E. coli cell growth occurs only in the presence of effective M2 channel inhibitors, and thus simple measurement of cell growth was used as readouts...

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Bibliografiske detaljer
Main Authors: Mao, Lili, Wang, Jun, DeGrado, William F., Inouye, Masayori
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542334/
https://ncbi.nlm.nih.gov/pubmed/23326573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054070
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