Leuprorelin Acetate Long-Lasting Effects on GnRH Receptors of Prostate Cancer Cells: An Atomic Force Microscopy Study of Agonist/Receptor Interaction

High cell-surface GnRH receptor (GnRH-R) levels have been shown to have a major influence on the extent of GnRH agonist-mediated tumor growth inhibition. The ability of the GnRH agonist leuprorelin acetate (LA) to induce a post-transcriptional upregulation of GnRH-R at the plasma membrane of androge...

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Главные авторы: Lama, Gina, Papi, Massimiliano, Angelucci, Cristiana, Maulucci, Giuseppe, Sica, Gigliola, De Spirito, Marco
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541369/
https://ncbi.nlm.nih.gov/pubmed/23326338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052530
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