Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel

BACKGROUND: Current protocols for the treatment of ovarian cancer include combination chemotherapy with a platinating agent and a taxane. However, many patients experience relapse of their cancer and the development of drug resistance is not uncommon, making successful second line therapy difficult...

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Hlavní autoři: Armstrong, Stephen R, Narendrula, Rashmi, Guo, Baoqing, Parissenti, Amadeo M, McCallum, Katherine L, Cull, Stephanie, Lannér, Carita
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541348/
https://ncbi.nlm.nih.gov/pubmed/23194409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-5-40
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