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Distinct genetic alterations occur in ovarian tumor cells selected for combined resistance to carboplatin and docetaxel
BACKGROUND: Current protocols for the treatment of ovarian cancer include combination chemotherapy with a platinating agent and a taxane. However, many patients experience relapse of their cancer and the development of drug resistance is not uncommon, making successful second line therapy difficult...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3541348/ https://ncbi.nlm.nih.gov/pubmed/23194409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-5-40 |
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