Interferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells

BACKGROUND: The type-II-cytokine IFN-γ is a pivotal player in innate immune responses but also assumes functions in controlling tumor cell growth by orchestrating cellular responses against neoplastic cells. The role of IFN-γ in melanoma is not fully understood: it is a well-known growth inhibitor o...

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Hlavní autoři: Schmitt, Martina J, Philippidou, Demetra, Reinsbach, Susanne E, Margue, Christiane, Wienecke-Baldacchino, Anke, Nashan, Dorothee, Behrmann, Iris, Kreis, Stephanie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541122/
https://ncbi.nlm.nih.gov/pubmed/23245396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-41
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