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The permeation of dynorphin A 1–6 across the blood brain barrier and its effect on bovine brain microvessel endothelial cell monolayer permeability

Dynorphin A 1–17 (Dyn A 1–17) is an endogenous neuropeptide known to act at the kappa opioid receptor; it has been implicated in a number of neurological disorders, including neuropathic pain, stress, depression, and Alzheimer’s and Parkinson’s diseases. The investigation of Dyn A 1–17 metabolism at...

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Detalhes bibliográficos
Main Authors: Sloan, Courtney D. Kuhnline, Audus, Kenneth L., Aldrich, Jane V., Lunte, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540977/
https://ncbi.nlm.nih.gov/pubmed/23046728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2012.09.031
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