Regeneration-associated WNT Signaling Is Activated in Long-term Reconstituting AC133(bright) Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is a genetically heterogeneous clonal disorder characterized by two molecularly distinct self-renewing leukemic stem cell (LSC) populations most closely related to normal progenitors and organized as a hierarchy. A requirement for WNT/β-catenin signaling in the pathogene...

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Detalhes bibliográficos
Main Authors: Beghini, Alessandro, Corlazzoli, Francesca, Del Giacco, Luca, Re, Matteo, Lazzaroni, Francesca, Brioschi, Matteo, Valentini, Giorgio, Ferrazzi, Fulvia, Ghilardi, Anna, Righi, Marco, Turrini, Mauro, Mignardi, Marco, Cesana, Clara, Bronte, Vincenzo, Nilsson, Mats, Morra, Enrica, Cairoli, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540948/
https://ncbi.nlm.nih.gov/pubmed/23308055
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