IRF-8 Controls Melanoma Progression by Regulating the Cross Talk between Cancer and Immune Cells within the Tumor Microenvironment

The transcription factor interferon regulatory factor-8 (IRF-8) is crucial for myeloid cell development and immune response and also acts as a tumor suppressor gene. Here, we analyzed the role of IRF-8 in the cross talk between melanoma cells and tumor-infiltrating leukocytes. B16-F10 melanoma cells...

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Main Authors: Mattei, Fabrizio, Schiavoni, Giovanna, Sestili, Paola, Spadaro, Francesca, Fragale, Alessandra, Sistigu, Antonella, Lucarini, Valeria, Spada, Massimo, Sanchez, Massimo, Scala, Stefania, Battistini, Angela, Belardelli, Filippo, Gabriele, Lucia
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540947/
https://ncbi.nlm.nih.gov/pubmed/23308054
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