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Expression of CCL19 from Oncolytic Vaccinia Enhances Immunotherapeutic Potential while Maintaining Oncolytic Activity

Promising phase II clinical results have been reported recently for several oncolytic viral therapeutics, including strains based on vaccinia virus. One reason for this has been an increased appreciation of the critical therapeutic importance of the immune response raised by these viruses. However,...

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Autori principali: Li, Jun, O'Malley, Mark, Sampath, Padma, Kalinski, Pawel, Bartlett, David L, Thorne, Steve H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540938/
https://ncbi.nlm.nih.gov/pubmed/23308044
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