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Profile of cabozantinib and its potential in the treatment of advanced medullary thyroid cancer

Medullary thyroid cancer is an uncommon malignancy for which until recently little effective treatment existed. It is often characterized by mutation and overexpression of the receptor tyrosine kinases RET (rearranged during transfection), VEGFR2 (vascular endothelial growth factor receptor 2) and M...

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Détails bibliographiques
Auteurs principaux: Hart, Christopher D, De Boer, Richard H
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540909/
https://ncbi.nlm.nih.gov/pubmed/23319867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S27671
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