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A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids

The fatty acid desaturase (FADS) genes code for the rate-limiting enzymes required for the biosynthesis of long-chain polyunsaturated fatty acids (LCPUFA). Here we report discovery and function of a novel FADS1 splice variant. FADS1 alternative transcript 1 (FADS1AT1) enhances desaturation of FADS2,...

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Detalhes bibliográficos
Main Authors: Park, Woo Jung, Kothapalli, Kumar S. D., Reardon, Holly T., Lawrence, Peter, Qian, Shu-Bing, Brenna, J. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540860/
https://ncbi.nlm.nih.gov/pubmed/22619218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M025312
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