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Metabolomics reveals an essential role for peroxisome proliferator-activated receptor α in bile acid homeostasis

Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor that regulates fatty acid transport and metabolism. Previous studies revealed that PPARα can affect bile acid metabolism; however, the mechanism by which PPARα regulates bile acid homeostasis is not understood. In this study,...

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Main Authors: Li, Fei, Patterson, Andrew D., Krausz, Kristopher W., Tanaka, Naoki, Gonzalez, Frank J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540854/
https://ncbi.nlm.nih.gov/pubmed/22665165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M027433
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