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Peripheral nerve injury produces a sustained shift in the balance between glutamate release and uptake in the dorsal horn of the spinal cord

Peripheral nerve injury provokes heightened excitability of primary sensory afferents including nociceptors, and elicits ectopic activity in lesioned and neighboring intact nerve fibers. The major transmitter released by sensory afferents in the superficial dorsal horn of the spinal cord is glutamat...

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Autors principals: Inquimbert, Perrine, Bartels, Karsten, Babaniyi, Olusegun B., Barrett, Lee B., Tegeder, Irmgard, Scholz, Joachim
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540793/
https://ncbi.nlm.nih.gov/pubmed/23021150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2012.08.011
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