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Angiotensin-converting enzyme inhibition curbs tyrosine nitration of mitochondrial proteins in the renal cortex during the early stage of diabetes mellitus in rats

Experiments were performed to evaluate the hypothesis that ACE (angiotensin-converting enzyme) inhibition (enalapril) suppresses 3-NT (3-nitrotyrosine) production in the renal cortex during the early stage of Type 1 DM (diabetes mellitus) in the rat. Enalapril was administered chronically for 2 week...

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Autors principals: Ishii, Naohito, Carmines, Pamela K., Yokoba, Masanori, Imaizumi, Hiroyuki, Ichikawa, Tsuyoshi, Ikenagasa, Hideki, Kodera, Yoshio, Oh-Ishi, Masamichi, Aoki, Yoshikazu, Maeda, Tadakazu, Takenaka, Tsuneo, Katagiri, Masato
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540783/
https://ncbi.nlm.nih.gov/pubmed/23130652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20120251
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