The Effect of D-(−)-arabinose on Tyrosinase: An Integrated Study Using Computational Simulation and Inhibition Kinetics

Tyrosinase is a ubiquitous enzyme with diverse physiologic roles related to pigment production. Tyrosinase inhibition has been well studied for cosmetic, medicinal, and agricultural purposes. We simulated the docking of tyrosinase and D-(−)-arabinose and found a binding energy of −4.5 kcal/mol for t...

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Autors principals: Liu, Hong-Jian, Ji, Sunyoung, Fan, Yong-Qiang, Yan, Li, Yang, Jun-Mo, Zhou, Hai-Meng, Lee, Jinhyuk, Wang, Yu-Long
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540692/
https://ncbi.nlm.nih.gov/pubmed/23365724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/731427
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