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Feasibility, safety and pharmacokinetic study of hepatic administration of drug-eluting beads loaded with irinotecan (DEBIRI) followed by intravenous administration of irinotecan in a porcine model

Irinotecan eluting embolization beads (DEBIRI) are currently being evaluated in the clinic for the treatment of colorectal cancer metastases to the liver. The aim of this study was to determine the safety and pharmacokinetics associated with two cycles of hepatic embolization using DEBIRI followed b...

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書誌詳細
主要な著者: Lewis, Andrew L., Holden, Rachel R., Chung, S. Ting, Czuczman, Peter, Kuchel, Timothy, Finnie, John, Porter, Susan, Foster, David
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540360/
https://ncbi.nlm.nih.gov/pubmed/23015264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10856-012-4768-2
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