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Functional dynamics in the active site of the ribonuclease binase

Binase, a member of a family of microbial guanyl-specific ribonucleases, catalyzes the endonucleotic cleavage of single-stranded RNA. It shares 82% amino acid identity with the well-studied protein barnase. We used NMR spectroscopy to study the millisecond dynamics of this small enzyme, using severa...

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Detalhes bibliográficos
Main Authors: Wang, Lincong, Pang, Yuxi, Holder, Tina, Brender, Jeffrey R., Kurochkin, Alexander V., Zuiderweg, Erik R. P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC35402/
https://ncbi.nlm.nih.gov/pubmed/11438724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.121069998
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