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Nano-assembly of Surfactants with Interfacial Drug-Interactive Motifs as Tailor-Designed Drug Carriers

PEGylated lipopeptide surfactants carrying drug-interactive motifs specific for a peptide-nitroxide antioxidant, JP4-039, were designed and constructed to facilitate the solubilization of this drug candidate as micelles and emulsion nanoparticles. A simple screening process based on the ability that...

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Main Authors: Gao, Xiang, Huang, Yixian, Makhov, Alexander M., Epperly, Michael, Lu, Jianqin, Grab, Sheila, Zhang, Peijun, Rohan, Lisa, Xie, Xiang-qun (Sean), Wipf, Peter, Greenberger, Joel, Li, Song
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540186/
https://ncbi.nlm.nih.gov/pubmed/23244299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300319m
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