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Vaccine-like and Prophylactic Treatments of EAE with Novel I-Domain Antigen Conjugates (IDAC): Targeting Multiple Antigenic Peptides to APC

The objective of this work is to utilize novel I-domain antigenic-peptide conjugates (IDAC) for targeting antigenic peptides to antigen-presenting cells (APC) to simulate tolerance in experimental autoimmune encephalomyelitis (EAE). IDAC-1 and IDAC-3 molecules are conjugates between the I-domain pro...

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Detalhes bibliográficos
Main Authors: Büyüktimkin, Barlas, Manikwar, Prakash, Kiptoo, Paul K., Badawi, Ahmed H., Stewart, John M., Siahaan, Teruna J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540176/
https://ncbi.nlm.nih.gov/pubmed/23148513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300440x
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