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Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition

The contractile phenotype and function of myofibroblasts have been proposed to play a critical role in wound closure. It has been hypothesized smooth muscle alpha-actin expressed in myofibroblasts is critical for their formation and function. We have used smooth muscle α-actin-null mice to test this...

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Autors principals: Tomasek, James J., Haaksma, Carol J., Schwartz, Robert J., Howard, Eric W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540133/
https://ncbi.nlm.nih.gov/pubmed/23253249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/wrr.12001
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