Nimotuzumab promotes radiosensitivity of EGFR-overexpression esophageal squamous cell carcinoma cells by upregulating IGFBP-3

BACKGROUND: Epidermal growth factor receptor (EGFR) is suggested to predict the radiosensitivity and/or prognosis of human esophageal squamous cell carcinoma (ESCC). The objective of this study was to investigate the efficacy of Nimotuzumab (an anti-EGFR monoclonal antibody) on ESCC radiotherapy (RT...

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Hlavní autoři: Zhao, Lei, He, Li-Ru, Xi, Mian, Cai, Mu-Yan, Shen, Jing-Xian, Li, Qiao-Qiao, Liao, Yi-Ji, Qian, Dong, Feng, Zi-Zhen, Zeng, Yi-Xin, Xie, Dan, Liu, Meng-Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540017/
https://ncbi.nlm.nih.gov/pubmed/23232108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-249
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