The L-type Ca(2+) Channels Blocker Nifedipine Represses Mesodermal Fate Determination in Murine Embryonic Stem Cells

Dihydropyridines (DHP), which nifedipine is a member of, preferentially block Ca(2+) channels of different cell types. Moreover, influx of Ca(2+) through L-type Ca(2+) channels (LTCCs) activates Ca(2+) signaling pathways, which in turn contribute to numerous cellular processes. Although LTCCs are ex...

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Detalhes bibliográficos
Main Authors: Nguemo, Filomain, Fleischmann, Bernd K., Gupta, Manoj K., Šarić, Tomo, Malan, Daniela, Liang, Huamin, Pfannkuche, Kurt, Bloch, Wilhelm, Schunkert, Heribert, Hescheler, Jürgen, Reppel, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539992/
https://ncbi.nlm.nih.gov/pubmed/23320083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053407
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