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Blood vessel hyperpermeability and pathophysiology in human tumour xenograft models of breast cancer: a comparison of ectopic and orthotopic tumours

BACKGROUND: Human tumour xenografts in immune compromised mice are widely used as cancer models because they are easy to reproduce and simple to use in a variety of pre-clinical assessments. Developments in nanomedicine have led to the use of tumour xenografts in testing nanoscale delivery devices,...

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Main Authors: Ho, Karyn S, Poon, Peter C, Owen, Shawn C, Shoichet, Molly S
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539979/
https://ncbi.nlm.nih.gov/pubmed/23217114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-579
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