Activation of antioxidant response element in mouse primary cortical cultures with sesquiterpene lactones isolated from Tanacetum parthenium

Tanacetum parthenium (Asteraceae) produces biologically active sesquiterpene lactones (SL). Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor known to activate a series of genes termed the antioxidant response element (ARE). Activation of the Nrf2/ARE may be useful for the treatmen...

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Detalhes bibliográficos
Main Authors: Fischedick, Justin T, Standiford, Miranda, Johnson, Delinda A., De Vos, Ric C.H., Todorović, Slađana, Banjanac, Tijana, Verpoorte, Rob, Johnson, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539777/
https://ncbi.nlm.nih.gov/pubmed/22923197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0032-1315241
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