Efficacy and safety of an extended nevirapine regimen in infant children of breastfeeding mothers with HIV-1 infection for prevention of postnatal HIV-1 transmission (HPTN 046): a randomised, double-blind, placebo-controlled trial

BACKGROUND: Nevirapine given once-daily for the first 6, 14, or 28 weeks of life to infants exposed to HIV-1via breastfeeding reduces transmission through this route compared with single-dose nevirapine at birth or neonatally. We aimed to assess incremental safety and efficacy of extension of such p...

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Autors principals: Coovadia, Hoosen M, Brown, Elizabeth R, Fowler, Mary Glenn, Chipato, Tsungai, Moodley, Dhayendre, Manji, Karim, Musoke, Philippa, Stranix-Chibanda, Lynda, Chetty, Vani, Fawzi, Wafaie, Nakabiito, Clemensia, Msweli, Lindiwe, Kisenge, Roderick, Guay, Laura, Mwatha, Anthony, Lynn, Diana J, Eshleman, Susan H, Richardson, Paul, George, Kathleen, Andrew, Philip, Mofenson, Lynne M, Zwerski, Sheryl, Maldonado, Yvonne
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539769/
https://ncbi.nlm.nih.gov/pubmed/22196945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(11)61653-X
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