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Synthesis studies on the Melodinus alkaloid meloscine

The pentacyclic Melodinus alkaloid (±)-meloscine was synthesized in 19 chemical steps from 2-bromobenzaldehyde through a route featuring an allenyl azide cyclization cascade to deliver the core azabicyclo[3.3.0]octane substructure. Peripheral functionalization of this core included a Tollens-type al...

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Détails bibliographiques
Auteurs principaux: Feldman, Ken S., Antoline, Joshua F.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539727/
https://ncbi.nlm.nih.gov/pubmed/23316092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2012.12.032
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