Blocking A(2B) Adenosine Receptor Alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis via Inhibition of IL-6 Production and Th17 Differentiation

Adenosine is a key endogenous signaling molecule that regulates immune responses. A(2B) adenosine receptor (AR) is a relatively low-affinity receptor for adenosine, and the activation of A(2B)AR is believed to require pathological level of adenosine that is associated with ischemia, inflammation, tr...

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Bibliographic Details
Main Authors: Wei, Wei, Du, Changsheng, Lv, Jie, Zhao, Guixian, Li, Zhenxin, Wu, Zhiying, Haskó, György, Xie, Xin
Format: Artigo
Language:Inglês
Published: AAI 2013
Subjects:
Immune Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539684/
https://ncbi.nlm.nih.gov/pubmed/23225885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103721
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