Palliative first-line therapy with weekly high-dose 5-fluorouracil and sodium folinic acid as a 24-hour infusion (AIO regimen) combined with weekly irinotecan in patients with metastatic adenocarcinoma of the stomach or esophagogastric junction followed by secondary metastatic resection after downsizing

BACKGROUND: The aim of this retrospective study was to evaluate the efficacy and safety of weekly high-dose 5-fluorouracil (5-FU)/folinic acid (FA) as 24-h infusion (AIO regimen) plus irinotecan in patients with histologically proven metastatic gastroesophageal adenocarcinoma (UICC stage IV). MATERI...

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Hauptverfasser: Koucky, Kathrin, Wein, Axel, Konturek, Peter C., Albrecht, Heinz, Reulbach, Udo, Männlein, Gudrun, Wolff, Kerstin, Ostermeier, Nicola, Busse, Dagmar, Golcher, Henriette, Schildberg, Claus, Janka, Rolf, Hohenberger, Werner, Hahn, Eckhart G., Siebler, Jürgen, Neurath, Markus F., Boxberger, Frank
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Scientific Literature, Inc. 2011
Schlagworte:
Clinical Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539586/
https://ncbi.nlm.nih.gov/pubmed/21525806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.881764
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