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The HER2 Receptor in Breast Cancer: Pathophysiology, Clinical Use, and New Advances in Therapy

Human epidermal growth factor receptor 2 (HER2) is overexpressed in around 20–30% of breast cancer tumors. It is associated with a more aggressive disease, higher recurrence rate, and increased mortality. Trastuzumab is a HER2 receptor blocker that has become the standard of care for the treatment o...

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Autors principals: Mitri, Zahi, Constantine, Tina, O'Regan, Ruth
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539433/
https://ncbi.nlm.nih.gov/pubmed/23320171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/743193
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