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Induction of the RNA Regulator LIN28A is Required for the Growth and Pathogenesis of RESTless Breast Tumors
The transcription factor REST is lost in approximately 20% of breast cancers. Although it is known that these “RESTless” tumors are highly aggressive and include all tumor subtypes, the underlying tumorigenic mechanisms remain unknown. In this study, we demonstrate that loss of REST results in up-re...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539431/ https://ncbi.nlm.nih.gov/pubmed/22532168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1639 |
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