Induction of the RNA Regulator LIN28A is Required for the Growth and Pathogenesis of RESTless Breast Tumors

The transcription factor REST is lost in approximately 20% of breast cancers. Although it is known that these “RESTless” tumors are highly aggressive and include all tumor subtypes, the underlying tumorigenic mechanisms remain unknown. In this study, we demonstrate that loss of REST results in up-re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gunsalus, Kearney T.W., Wagoner, Matthew P., Meyer, Kassondra, Potter, Wyatt B., Schoenike, Barry, Kim, Soyoung, Alexander, Caroline M., Friedl, Andreas, Roopra, Avtar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539431/
https://ncbi.nlm.nih.gov/pubmed/22532168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1639
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg