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Halogenated Pentamethine Cyanine Dyes Exhibiting High Fidelity for G-Quadruplex DNA

Design and optimization of quadruplex-specific small molecules is developing into an attractive strategy for anti-cancer therapeutics with some promising candidates in clinical trials. A number of therapeutically favorable features of cyanine molecules can be effectively exploited to develop them as...

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Detalhes bibliográficos
Main Authors: Nanjunda, Rupesh, Owens, Eric A., Mickelson, Leah, Alyabyev, Sergey, Kilpatrick, Nancy, Wang, Siming, Henary, Maged, Wilson, W. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539309/
https://ncbi.nlm.nih.gov/pubmed/23127491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.10.008
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