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Fibronectin regulates Wnt7a signaling and satellite cell expansion

The influence of the extracellular matrix (ECM) within the stem cell niche remains poorly understood. We found that Syndecan-4 (Sdc4) and Frizzled-7 (Fzd7) form a co-receptor complex in satellite cells and that binding of the ECM glycoprotein Fibronectin (FN) to Sdc4 stimulates the ability of Wnt7a...

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Détails bibliographiques
Auteurs principaux: Bentzinger, C. Florian, Wang, Yu Xin, von Maltzahn, Julia, Soleimani, Vahab D., Yin, Hang, Rudnicki, Michael A.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539137/
https://ncbi.nlm.nih.gov/pubmed/23290138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.09.015
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