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Inhibition of host protein synthesis in vaccinia virus-infected cells in the presence of cordycepin (3'-deoxyadenosine).

Cordycepin inhibited efficiently viral mRNA and polyadenylic acid syntheses in vaccinia virus-infected cells, but allowed the shutoff of host protein synthesis to occur. Therefore, cordycepin was used to study this shutoff in the absence of gene expression. Ribosome transit time was increased in inf...

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Bibliographic Details
Main Authors: Person, A, Beaud, G
Format: Artigo
Language:Inglês
Published: 1978
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC353895/
https://ncbi.nlm.nih.gov/pubmed/304489
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