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Investigation of Zr(IV) and (89)Zr(IV) complexation with hydroxamates: Progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging

Single crystal X-ray diffraction show that Zr(IV) forms an octa-coordinated complex with 4 bidentate hydroxamates whose solution structures were investigated utilizing density functional theory at the level of B3LYP/DGDZVP. Stability constants obtained by potentiometry were in accordance with the te...

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Detalhes bibliográficos
Main Authors: Guérard, François, Lee, Yong-Sok, Tripier, Raphaël, Szajek, Lawrence P., Deschamps, Jeffrey R., Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538910/
https://ncbi.nlm.nih.gov/pubmed/23250287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc37549d
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