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Sortase-conjugation generates a capsule vaccine that protects guinea pigs against Bacillus anthracis
Capsules protect bacteria against phagocytic clearance. Capsular polysaccharides or polyglutamates have evolved also to resist antigen presentation by immune cells, thereby interfering with the production of opsonophagocytic antibodies. Linking capsular material to a carrier protein stimulates its p...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538850/ https://ncbi.nlm.nih.gov/pubmed/22449424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.03.023 |
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